Choyamba, matrine ndi mankhwala opangidwa ndi mbewu omwe ali ndi mawonekedwe achilengedwe. Zimangokhudza zamoyo zina ndipo zimatha kuwonongeka mwachangu. Chotsatira chake ndi carbon dioxide ndi madzi. Kachiwiri, matrine ndi mankhwala amtundu wokhazikika omwe amalimbana ndi zinthu zovulaza. Zomwe zimapangidwazo sizophatikizira chimodzi, koma kuphatikiza kwamagulu angapo okhala ndi mankhwala ofanana ndi magulu angapo okhala ndi mitundu yosiyana yamankhwala, yomwe imathandizana ndikugwira ntchito limodzi. Chachitatu, matrine atha kugwiritsidwa ntchito kwa nthawi yayitali chifukwa chophatikizika kwa zinthu zosiyanasiyana zamankhwala, zomwe zimapangitsa kuti zikhale zovuta kuyambitsa kukana zinthu zovulaza. Chachinayi, tizirombo tofananako sidzaphedwa poizoni mwachindunji, koma kuwongolera anthu tizirombo sikungakhudze kwambiri kuchuluka kwa mbeu. Njirayi ndi yofanana kwambiri ndi njira yothetsera tizilombo mu njira zonse zopewera ndi kuwongolera zomwe zapangidwa patatha zaka makumi angapo kuchokera patachitika zotsatira zoyipa za chitetezo cha mankhwala. Mfundo zinayi zomwe zatchulidwazi zitha kuwonetsa kuti matrine mwachiwonekere ndiwosiyana ndi mankhwala ophera tizilombo owopsa kwambiri, ndipo ndi obiriwira komanso osasamalira zachilengedwe.